Pipeline

ProgramIndicationPreclinicalPhase 1Phase 2Phase 3Expected Key Milestones
Pacibekitug Thyroid Eye Disease (TED)
 

Phase 2b topline data expected in H2 2025

Phase 3 expected to begin in H2 2024

Atherosclerotic Cardiovascular Disease (ASCVD)
 

Phase 2 topline data expected in H1 2025

Pacibekitug
Thyroid Eye Disease (TED)
PreclinicalPhase 1Phase 2Phase 3
Expected Key Milestone:

Phase 2b topline data expected in H2 2025

Phase 3 expected to begin in H2 2024

Pacibekitug
Atherosclerotic Cardiovascular Disease (ASCVD)
PreclinicalPhase 1Phase 2Phase 3
Expected Key Milestone:

Phase 2 topline data expected in H1 2025

We continue to seek additional opportunities for pacibekitug (also known as TOUR006). We continue to identify indications where IL-6 inhibition has shown evidence of clinical benefit despite no formal industry-led development programs as well as indications where we could bring pacibekitug’s differentiated profile forward, capitalizing on external de-risking events.

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